Methyl-Guard Plus®

Methyl-Guard Plus®

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Support cellular energy production, heart and brain health, and a positive mood with key nutrients that help optimize methylation.*

Methyl-Guard Plus delivers powerful methyl donors—including trimethylglycine, 5-MTHF, and methylcobalamin—along with the bioactive forms of vitamins B2 and B6. Together, these nutrients form a comprehensive formula designed to support whole-body methylation and overall metabolic health.*

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Description

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Various factors such as nutrient deficiencies, environmental stressors, and modern lifestyle habits can negatively affect the body’s methylation cycle. Additionally, a significant portion of adults carry genetic variations (such as MTHFR) that may reduce methylation efficiency.

Thorne Methyl-Guard Plus is designed to provide comprehensive nutritional support for healthy methylation. It combines betaine (trimethylglycine), active forms of vitamin B12 (methylcobalamin) and folate (5-MTHF), along with the biologically active forms of vitamins B2 and B6 to support optimal metabolic function.

Key Benefits

  • Supports individuals with MTHFR and other genetic variations affecting methylation*
  • Helps maintain healthy homocysteine levels, supporting heart, brain, and bone health*
  • Promotes cellular energy production and helps reduce occasional fatigue*
  • Supports fat metabolism and healthy body composition*
  • Aids neurotransmitter production, supporting focus, mood, attention, and sleep*
  • Supports liver detoxification processes, including hormone (estrogen) metabolism*

Why Methylation Matters

Methylation is a fundamental biochemical process where methyl groups are transferred between molecules. It plays an essential role in:

  • Cardiovascular and neurological health
  • Cellular energy production
  • DNA synthesis and repair
  • Fat metabolism
  • Liver detoxification
  • Hormonal balance
  • Immune and histamine regulation

Who May Benefit

  • Individuals with MTHFR or related genetic variations
  • Adults seeking support for cardiovascular, cognitive, and metabolic health
  • Women looking to support estrogen metabolism and bone health
  • Those aiming to improve fat metabolism and body composition
  • People with low intake of methylation-supportive foods like leafy greens and legumes

Product Features

  • Contains betaine (TMG), a powerful methyl donor
  • Uses active, bioavailable forms of folate and vitamin B12
  • Includes active B2 and B6 as essential methylation cofactors
  • High-potency formula in fewer capsules per day than the original Methyl-Guard
  • Third-party tested for quality, purity, and safety, ensuring no harmful contaminants

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