SAMe + CoFactors 200mg

SAMe with Cofactors – Mood, Liver & Methylation Support
Boost your mood, liver health, and methylation with this advanced formula. Each serving delivers 400 mg of SAMe plus active B-vitamins—methylcobalamin, L-5-MTHF, and P-5-P—to support neurotransmitter balance, cognitive clarity, and healthy detox pathways.* Gluten- and soy-free, designed for immediate absorption and optimal results.*

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Description

SAMe with Cofactors – Mood, Liver & Methylation Support

Supports mood balance, liver health, and optimal methylation with a potent blend of nutrients.

What is SAMe with Cofactors?

SAMe with Cofactors is a scientifically formulated dietary supplement designed to support balanced mood, cognitive clarity, healthy liver function, and efficient methylation. Combining S-adenosyl-L-methionine (SAMe) with essential methyl donors and active B-vitamins, this advanced formula promotes neurotransmitter synthesis, cellular detoxification, and energy metabolism.*

Key Benefits

  • Mood Support: Helps maintain healthy serotonin, dopamine, and norepinephrine levels for emotional balance.*

  • Liver Health: Supports liver detoxification and phospholipid synthesis.*

  • Methylation Support: Provides active B-vitamins and cofactors to optimize methylation pathways, homocysteine metabolism, and overall cellular health.*

  • Cognitive Clarity: Supports mental focus and neurochemical balance for enhanced brain function.*

How SAMe with Cofactors Works

  • SAMe (S-adenosyl-L-methionine): A universal methyl donor that promotes healthy neurotransmitter metabolism and liver detoxification.* [1,2]

  • L-5-Methylfolate: The active form of folate essential for remethylation of homocysteine and neurotransmitter production.* [3,4]

  • Vitamin B12 (Methylcobalamin): Supports nerve health, red blood cell formation, and methylation balance alongside folate and SAMe.* [4,5]

  • Vitamin B6 (Pyridoxal-5′-Phosphate): Acts as a coenzyme in amino acid metabolism and aids in the synthesis of serotonin, GABA, and dopamine.* [5]

Who Should Take SAMe with Cofactors?

Ideal for anyone looking to:

  • Support mood balance and emotional well-being

  • Enhance liver function and detoxification

  • Boost cognitive clarity and mental focus

  • Address increased methylation demands due to stress, genetics, or lifestyle factors

Special Features

  • Contains bioactive B-vitamins: methylcobalamin, L-5-MTHF, and P-5-P for immediate absorption

  • 400 mg of SAMe per serving to support optimal methylation

  • Gluten- and soy-free

  • Manufactured under strict quality standards for purity and potency

References

  1. Baden KER, et al. Nutrients. 2024;16(18):3148. doi:10.3390/nu16183148

  2. Baden K, et al. Nutrients. 2024;16(21):3668. doi:10.3390/nu16213668

  3. Papakostas GI, et al. Am J Psychiatry. 2012;169(12):1267-74.

  4. Reynolds E. Lancet Neurol. 2006;5(11):949-60.

  5. Kennedy DO. Nutrients. 2016;8(2):68

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