SAMe + CoFactors 200mg
SAMe with Cofactors – Mood, Liver & Methylation Support
Boost your mood, liver health, and methylation with this advanced formula. Each serving delivers 400 mg of SAMe plus active B-vitamins—methylcobalamin, L-5-MTHF, and P-5-P—to support neurotransmitter balance, cognitive clarity, and healthy detox pathways.* Gluten- and soy-free, designed for immediate absorption and optimal results.*
Description
SAMe with Cofactors – Mood, Liver & Methylation Support
Supports mood balance, liver health, and optimal methylation with a potent blend of nutrients.
What is SAMe with Cofactors?
SAMe with Cofactors is a scientifically formulated dietary supplement designed to support balanced mood, cognitive clarity, healthy liver function, and efficient methylation. Combining S-adenosyl-L-methionine (SAMe) with essential methyl donors and active B-vitamins, this advanced formula promotes neurotransmitter synthesis, cellular detoxification, and energy metabolism.*
Key Benefits
-
Mood Support: Helps maintain healthy serotonin, dopamine, and norepinephrine levels for emotional balance.*
-
Liver Health: Supports liver detoxification and phospholipid synthesis.*
-
Methylation Support: Provides active B-vitamins and cofactors to optimize methylation pathways, homocysteine metabolism, and overall cellular health.*
-
Cognitive Clarity: Supports mental focus and neurochemical balance for enhanced brain function.*
How SAMe with Cofactors Works
-
SAMe (S-adenosyl-L-methionine): A universal methyl donor that promotes healthy neurotransmitter metabolism and liver detoxification.* [1,2]
-
L-5-Methylfolate: The active form of folate essential for remethylation of homocysteine and neurotransmitter production.* [3,4]
-
Vitamin B12 (Methylcobalamin): Supports nerve health, red blood cell formation, and methylation balance alongside folate and SAMe.* [4,5]
-
Vitamin B6 (Pyridoxal-5′-Phosphate): Acts as a coenzyme in amino acid metabolism and aids in the synthesis of serotonin, GABA, and dopamine.* [5]
Who Should Take SAMe with Cofactors?
Ideal for anyone looking to:
-
Support mood balance and emotional well-being
-
Enhance liver function and detoxification
-
Boost cognitive clarity and mental focus
-
Address increased methylation demands due to stress, genetics, or lifestyle factors
Special Features
-
Contains bioactive B-vitamins: methylcobalamin, L-5-MTHF, and P-5-P for immediate absorption
-
400 mg of SAMe per serving to support optimal methylation
-
Gluten- and soy-free
-
Manufactured under strict quality standards for purity and potency
References
-
Baden KER, et al. Nutrients. 2024;16(18):3148. doi:10.3390/nu16183148
-
Baden K, et al. Nutrients. 2024;16(21):3668. doi:10.3390/nu16213668
-
Papakostas GI, et al. Am J Psychiatry. 2012;169(12):1267-74.
-
Reynolds E. Lancet Neurol. 2006;5(11):949-60.
-
Kennedy DO. Nutrients. 2016;8(2):68
Only logged in customers who have purchased this product may leave a review.




Reviews
There are no reviews yet.